Agilent 7200 QTOF GC-MS with 7693 Autosampler

Overview

The Agilent 7200 QTOF GC-MS with 7693 Autosampler is a quadrupole time-of-flight gas chromatography–mass spectrometry system designed for high-resolution accurate-mass analysis of volatile and semi-volatile compounds. By combining quadrupole mass filtering with time-of-flight detection, the instrument supports both qualitative screening and structural confirmation work in a single platform. The integrated 7693 autosampler adds automated, unattended sample introduction, making the system suited to laboratories that process large numbers of samples and require consistent, reproducible injections.

Mass Analysis and Detection

The QTOF analyzer covers a mass range of 20 to 1700 m/z, allowing detection across a broad spectrum of low- and higher-mass analytes. With mass resolution of up to 40,000 FWHM, the system is capable of resolving closely spaced ions and supporting accurate-mass measurement that aids in compound identification and formula assignment. A scan speed of up to 50 spectra per second enables data collection across narrow chromatographic peaks, which is important when working with fast GC separations or complex sample matrices.

Ionization is performed using an Electron Ionization (EI) source. EI produces reproducible, library-comparable fragmentation patterns, making it a standard choice for the analysis of small organic molecules and for matching against established spectral databases.

Automated Sampling with the 7693 Autosampler

The 7693 autosampler provides automated handling of samples to reduce manual intervention and improve run-to-run consistency. Each tray holds 16 vials, and the system can be configured with multiple trays to accommodate up to 150 samples in a single sequence. For samples requiring thermal protection, the autosampler offers cooling across a temperature range of 4°C to 40°C, helping preserve sensitive analytes prior to injection.

• Mass Range: 20 to 1700 m/z
• Mass Resolution: Up to 40,000 FWHM
• Scan Speed: Up to 50 spectra/second
• Ionization Source: Electron Ionization (EI)
• Autosampler Capacity: 16 vials per tray, up to 150 samples with multiple trays
• Sample Cooling Range: 4°C to 40°C
• Data Acquisition Rate: Up to 4 GB/day

Data Handling and Applications

The system supports a data acquisition rate of up to 4 GB/day, reflecting its capacity to capture the high-density, full-spectrum datasets generated by high-resolution time-of-flight acquisition. This depth of data is valuable for retrospective analysis, where previously acquired runs can be re-interrogated for compounds that were not originally targeted.

Typical applications for an EI-based QTOF GC-MS platform include environmental analysis, food and flavor profiling, metabolomics, forensic and toxicology screening, and general unknown identification in research settings. The combination of accurate-mass detection, fast scanning, and automated sample introduction makes the Agilent 7200 QTOF GC-MS with 7693 Autosampler a practical choice for laboratories that need both confirmatory accuracy and sustained sample throughput.